Detection and neutralization of biotoxins represent significant challenges that are desperately needed for the protection of public health, environmental safety and national security. They are natural or artificial poisons that pose a significant risk due to their extreme toxicity and ability to disperse quickly. Nanotechnology is an area which can address these kinds of issues, offering the ability to manipulate materials at the nanoscale. Here, we review recent developments in the biosensing and detoxification of biotoxins, as well as the critical participation of nanotechnology during that process. The use of nanomaterials, including gold nanoparticles, quantum dots, carbon nanotubes, and magnetic nanoparticles, has improved the sensitivity and specificity of detection methods. Additionally, catalytic nanomaterials and targeted delivery systems hold considerable potential for biotoxin neutralization. These advancements are not free of challenges. Nanotechnology of biotoxins has many advantages, and the author mentions some future research directions of these biomolecules; which not only improve biosafety but also bio-efficacy

Nanotechnology, Biotoxins, Detection, Neutralization, Nanomaterials, Public Health

As nanotechnology offers improved sensitivity, specificity, and efficiency, it has the potential to completely transform the detection and neutralisation of biotoxins. Rapid and accurate detection of dangerous poisons is made possible by the use of nanoparticles in biosensing devices, such as carbon nanotubes, quantum dots, and gold nanoparticles. Furthermore, effective countermeasures in defence, environmental, and medical applications are made possible by nanotechnology's participation in biotoxin neutralisation mechanisms such adsorption, targeted distribution, and catalytic degradation. The broad adoption of these technologies will be accelerated as research advances by the creation of biocompatible nanomaterials, their incorporation with artificial intelligence, and advancements in scalability and cost-effectiveness. A viable avenue for preserving environmental protection, human health, and national security is the use of nanotechnologies in biotoxin monitoring and neutralisation

Saba Rana, Vipin Kumar Saini, Shalini Mishra, Vikas Kumar, Ashu Chaudhary and Zehra Husaini (2025). International Journal of Theoretical & Applied Sciences, 17(1): 56-59