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Author: Kumar A., Singh V.P. and Singh S.

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Abstract

The treatment protocols of carcinoma is dependent upon disease staging, tumor characteristics such as- metastasis, status of molecular markers like ER, PR and HER2 new. Treatment protocols involve, surgery, chemotherapy and radiotherapies and combinations of all three. This review article deals with various chemotherapeutic protocols which are being tested under various clinical trials and their mechanisms of actions. Standard chemotherapy treatments lack the ability to distinguish between healthy cells and cancerous cells. As a result, they can lead to significant side effects that are frequently more distressing than the actual cancer. Also, recent advancement as immunotherapy inclusion has also been included. We will now provide an overview of the ongoing efforts in developing dynamic biomarkers for treatment response.

Keywords

Breast carcinoma, chemotherapy, protocols, treatment. Modified radical mastectomies, breast conserving surgeries, oncoplastic breast surgery

Conclusion

Chemotherapeutic protocols in various stages of breast carcinoma are met by challenges such as induction of side effects, development of drug resistance and also, residual disease. During last few years, multiple protocols have been studied and experimented upon in form of clinical trials to test the efficacy as well as less morbid situations. Recently, immunotherapy has been ventured upon but promising results are yet to be ascertained. Thus, it remains a subject of continuous trials where the challenge of reducing the disease burden remains.

References

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How to cite this article

Kumar A., Singh V.P. and Singh S. (2023). Update on Treatment Protocols in Breast Carcinoma. Biological Forum – An International Journal, 15(5): 1243-1246.