Antidiabetic activities of leaves extracts of Justicia adhatoda L. (Malabar nut) in rats

Author: Rachana, M. N., Sharanagouda Hiregoudar, Udaykumar Nidoni, Ramappa, K. T., Sushila Nadagouda and Nagaraj Naik

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Abstract

Justicia adhatoda has been used for the treatment of various diseases and disorders. It is a primary medicinal plant for the respiratory tract ailments in the treatment of cough, bronchitis, asthma and symptoms of common cold. The Supercritical fluid extract of Justicia adhatoda in Group V (49.05%) and Group VII (47.95%) higher doses exhibited excellent antidiabetic property in albino mice.

Keywords

Justicia adhatoda, diabetes mellitus, blood glucose, supercritical fluid extraction, albino mice

Conclusion

The investigation was focused on to screening of antidiabetic activity of Justicia adhatoda leaves (JAL) ethanolic-extract and its fractions (JAL-F). The result of the present study demonstrates the efficiency JAL ethanolic extract and fraction. Ethanolic extract of Justicia adhatoda is lowering the serum glucose level in STZ induced diabetic rat models. The SFE extract of Justicia adhatoda in Group V (49.05%) and Group VII (JBL-F 47.95%) higher doses exhibited excellent antidiabetic property at 3rd week. The Ethanolic extracts of Justicia adhatoda fractions and (JAL-F) treated groups showed better decrease in blood glucose level when compared with control group. Hence Justicia adhatoda extract and fraction are to be claimed as a good antidiabetic natural bioactive compound.

References

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How to cite this article

Rachana, M. N., Sharanagouda Hiregoudar, Udaykumar Nidoni, Ramappa, K. T., Sushila Nadagouda and Nagaraj Naik (2023). Antidiabetic activities of leaves extracts of Justicia adhatoda L. (Malabar nut) in rats. Biological Forum – An International Journal, 15(10): 778-780.