Biosynthesis of Zinc Oxide Nanoparticle using the cyanobacterium Chlorogloeopsis fritschii BK (MN968818) Isolated from the Mangrove Environment of Kendrapara, Odisha and Evaluation of its Antibacterial Property

Author: Radhakanta Nag, Himansu Sekhar Sahoo and Saubhagya Manjari Samantaray*

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Abstract

Multidrug resistance of bacteria towards antibiotics is a critical issue that must be addressed urgently and efficiently. In this context, nanoparticles can be opted as a suitable alternative for treating bacterial diseases. Recently, biosynthesized metal nanoparticles have been recommended as viable alternatives as their methods of preparations are precise and environmental-friendly for a cost-effective scale-up. For the biosynthesis of nanoparticles, a greater diversity of microbiota has been used, among which cyanobacteria are considered a valuable source due to their bioactive compound contents. In this regard, a cyanobacterium is identified as Chlorogloeopsis fritschii BK (MN968818) by 16S rRNA sequencing, isolated from the Mahanadi mangrove environment of Kendrapara, Odisha. It has been used for ZnO NPs synthesis in vitro. Moreover, the biosynthesized ZnO NPs are characterized by UV-Vis spectroscopy, X-ray diffraction (XRD), zeta potential measurement, FTIR, SEM-EDS. The antiba

Keywords

Biosynthesis, mangrove environment, cyanobacterium, indigenous, ZnO NP, antibacterial assay.

Conclusion

The utilization of cyanobacteria has paved the way for green nanotechnology, lowering the generation of unwanted and impure chemicals. The present study lays the groundwork for future research into our understanding of how the aqueous extract of Chlorogloeopsis fristchii BK (MN968818) collected from the Mahanadi Delta mangrove region can be used as a reducing and capping agent for the biosynthesis of ZnO NPs. The ZnO NPs characterized by UV–Vis spectroscopy, FTIR, XRD, SEM-EDS, and DLS analysis. The biosynthesized ZnO NPs demonstrated significant antibacterial activities against B. cereus (MCC 1086) and E. coli (MCC3671) in comparison to the standard antibiotic ampicillin with sulbactam. The green synthesis and high efficacy of the cyanobacterium Chlorogloeopsis fristchii BK (MN968818) for ZnO NPs synthesis may be helpful for its applications as an antibacterial agent to treat the infection caused by B. cereus (MCC 1086) and E. coli (MCC 3671). The benefits of using cyanobacterium

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How to cite this article

Radhakanta Nag, Himansu Sekhar Sahoo and Saubhagya Manjari Samantaray (2022). Biosynthesis of Zinc Oxide Nanoparticle using the cyanobacterium Chlorogloeopsis fritschii BK (MN968818) Isolated from the Mangrove Environment of Kendrapara, Odisha and Evalu