Cytotoxic effects of Cabbage (Brassica oleracea var. capitata) Leaves extract on the Root Meristematic Cells of Vicia faba L.

Author: Amit Vaish

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Abstract

Cabbage leaves are consumed as a vegetable all over the world. This member of family Brassicaceae is a popular ingredient of international salad. It is a rich source of vitamins and minerals but its over consumption may hamper human health also. In this study the investigator has tried to find out the possible cytotoxic effects of cabbage leaves aqueous extract on meristematic cells of Vicia faba L. Actively growing root tips of Vicia faba L. were treated with 100%, 75%, 50%, 25% and 10% concentrations of cabbage leaves extract for 2, 4 and 6 hours. The results obtained showed that the cabbage leaves extract is mitodepressive in nature and induces various types of chromosomal and nuclear aberrations such as multinucleate cells, stickiness at metaphase, disturbed metaphases, scattered metaphases, chromatid separation, polarity abolition, laggards and bridges at anaphases and telophases. It is concluded that cabbage leaves extract not only affect mitotic activity but also shows adverse impact on chromosomal behaviour of cells.

Keywords

Cabbage, Chromosomal and nuclear aberrations, Cytotoxic

Conclusion

The investigator concluded that the cabbage (Brassica oleracea var. capitata) leaves extract not only inhibits mitotic activity but also induces various nuclear and chromosomal aberrations. From this investigation it can be concluded that the raw cabbage should not be consumed as it causes mitotic inhibition in Vicia faba root tip cells. Some researchers also indicated that Brassica vegetables contain DNA damaging compounds. The author is of opinion that cabbage leaves must be further investigated for their mitodepressive and mutagenic potential.

References

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How to cite this article

Amit Vaish (2023). Cytotoxic effects of Cabbage (Brassica oleracea var. capitata) Leaves extract on the Root Meristematic Cells of Vicia faba L. Biological Forum – An International Journal, 15(5): 1293-1298.