Effect of Mastacembelus Armatus Epidermal Mucus Extracts on Selected Urinary Tract Infection Pathogens

Author: R. Sivasakthi, S. Uma Rajeswari and M. Umamageshwari

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Abstract

The developing bacterial resistance counter agents of antimicrobials have led to the research for alternatives to traditional antibiotics. The fish mucus comprises different antimicrobial representatives that serve as a first defence line to counter numerous pathogens of invading. The modern work was considered for evaluating the outcome of Mastacembelus armatus epidermal mucus on selected urinary tract infection (UTI) causing bacteria (Staphylococcus epidermidis, staphylococcus hominis, and proteus mirabilis, Enterobacter cloacae, Escherichia coli, Enterococcus avium, Pseudomonas aeruginosa) and fungi (Candida albicans). The selected UTI pathogens were treated with acetic acid, Aqueous and organic epidermal mucus subtracts gathered in the container of Mastacembelus armatus at 12.5, 25 and 50 along with 100µg/mL. The acidic mucus extract showed novel antibiotic activity against the selected UTI pathogens, followed by aqueous and organic mucus subtracts. Moreover, the acidic epidermal mucus extract of Mastacembelus armatus, at 100 µg/mL, displayed the highest zone of inhibition for Escherichia coli, followed by Candida albicans, Pseudomonas aeruginosa, Staphylococcus epidermidis, Proteus mirabilis, Staphylococcus hominis, Enterobacter cloacae and Enterococcus avium, respectively. Moreover, the values of MIC extended between 25 and 50 µg/mL, as well as the amounts of MBC scaled from 100 µg/mL and 50 µg/mL. For acidic epidermal mucus extract against selected UTI pathogens. The current findings presented that the epidermal mucus of acidic “Mastacembelus armatus processes” novel antimicrobial actions counter pathogens of UTI.

Keywords

Fish mucus, Activity of Antimicrobial, Tract of urinary infection, Mastacembelus armatus

Conclusion

The present study presented the acidic mucus extracts of Mastacembelus armatus possess novel antimicrobial activity against selected UTI pathogens than organic and aqueous mucus extracts. This indicates the presence of antimicrobial bioactive compounds / peptides / proteins in the mucus of Mastacembelus armatus. Therefore, further investigation is required to identify and isolate the individual antimicrobial compounds / peptides / proteins from the mucus of Mastacembelus armatus.

References

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How to cite this article

Sivasakthi, R., Uma Rajeswari, S. and Umamageshwari. M. (2023). Effect of Mastacembelus armatus epidermal mucus extracts on selected urinary tract infection pathogens. Biological Forum – An International Journal, 15(4): 518-525.