Evaluation and Investigation of the Antidiabetic Effect of Aqueous and Hydroalcoholic Extract of Elaeocarpus ganitrus (Rudraksha)

Author: Subhashish Tripathy, Amit Mishra and Arun Kumar Mishra

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Abstract

This experimental study investigated the antidiabetic effect of aqueous and hydroalcoholic extract of the Elaeocarpus ganitrus (Rudraksha) plant, which is usually used to cure many diseases due to its electromagnetic property. Diabetic was induced in fasted rats by inducing a single intraperitoneal injection of 150 mg Kg-1 of Alloxan monohydrate. Two doses (550 and 1050mg Kg-1) of these aqueous and hydroalcoholic extracts of Elaeocarpus ganitrus were administrated orally to diabetic rats. The standard control group receives distilled water only. After half a month (15 days) of treatment, body weight gain, blood glucose level, Serum insulin other body metabolites were studied and evaluated for Diabetic. It was noticed that at tested doses, aqueous and hydroalcoholic extract of Elaeocarpus ganitrus decreased blood glucose levels significantly after half month of administration. The aqueous extract reduces body weight gain, contrary to the hydroalcoholic section. Increase Serum insulin level compared in the group, treated group and diabetic control group. The hydroalcoholic extract reduces the monohydrate concentration in Serum. Values of total cholesterol and triglyceride are similar in all groups. This study demonstrated the potential antidiabetic property of aqueous and hydroalcoholic extract of Elaeocarpus ganitrus. thus justifying its traditional usage. The purpose of this research is to understand the antidiabetic effects of Rudraksha and gain an understanding of the challenges faced by novice researchers and students when examining the antidiabetic effects of the Elaeocarpus ganitrus plant. Research has improved the globe by addressing the issue of therapeutic Rudraksha use that is currently present.

Keywords

Rudraksha, Elaeocarpus ganitrus, blood glucose, insulin, antidiabetic effect

Conclusion

The experimental study concluded that the Elaeocarpus ganitrus extract exhibited antidiabetic activity by stimulating serum insulin levels in Alloxan-influenced rats. This exploratory study shows that Elaeocarpus ganitrus can help in the treatment of diabetes and the prevention of its complication. For a better understanding of the results, further scientific research may encourage new researchers in this field.

References

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How to cite this article

Subhashish Tripathy, Amit Mishra and Arun Kumar Mishra (2023). Evaluation and Investigation of the Antidiabetic Effect of Aqueous and Hydroalcoholic Extract of Elaeocarpus ganitrus (Rudraksha). Biological Forum – An International Journal, 15(5): 367-371.