Evaluation of Phytochemical Analysis and In vitro Antioxidant activities of Stem and Leaf extract of Andrographis echioides (L.) Nees

Author: Ranjani N., Kannan R., Kokila D., Bhuvaneswari V. and Vishnu Kumar S.

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Abstract

Plants are essential to human life on Earth and serve as its foundation. Their therapeutic uses are another important aspect of plants. Medicinal plants provide an excellent source of lead compounds for the finding new drugs with few adverse reactions, which is a very respectable source. The Andrographis echioides is a highly medicinal valuable plant widely spread in south India. The plant general name is called as “false water willow”. The objective of the current study is to assess the in vitro antioxidant activity, quantitatively estimating, and qualitative phytochemical evaluation of different extraction of the Andrographis echioides both leaves and stems. The dried leaf while stem powders of Andrographis echioides was phytochemically analyzed, and it was found to include carbohydrates, proteins, amino acids, alkaloids, saponins, phenols, flavonoids, glycosides, cardiac glycosides, fixed fats and oils, gums, and Musilages. The DPPH, FRAP, Reducing Power, and Phosphoromolybdenum tests methods were utilized to investigate phytochemicals and in vitro antioxidant capabilities. The traditional usage of Andrographis echioides as a complementary medicine for treating specific medical disorders is supported by the presence of phytochemical components. Additional research should be done to extract particular phytochemical chemical ingredients, and these compounds should then be used in various studies to examine their biological impacts. A medicinal plant called Andrographis echioides is used to cure a variety of diseases. It may have antioxidant qualities. Finding a novel herbal remedy for oxidative stress from Andrographis echioides is the goal of the current research.

Keywords

DPPH, FRAP, Phytochemicals, Andrographis echioides, Reducing power assay, Secondary metabolites, Phosphomolybdenum

Conclusion

The phytochemical components and in vitro antioxidant activity are screened in the leaves and stems of Andrographis echioides. Utilising various solvents and their polar nature, phytochemicals and in vitro anti-oxidant properties are estimated. The Ethyl acetate extract of the stem contained the highest concentration of antioxidants found in the plant and the greatest number of secondary metabolites. The examination is particularly beneficial for creating novel medications to treat a variety of diseases. According to the analysis mentioned earlier, the plant has a great deal of potential to be exploited in drugs and as a potential source of significant medicines. Because it contains several phytocompounds that are essential for good health, it can be used to improve society's overall health. Research is currently being performed to uncover innovative, dynamic, and unique remedies for a number of serious diseases that have lately been identified.

References

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How to cite this article

Ranjani N., Kannan R., Kokila D., Bhuvaneswari V. and Vishnu Kumar S. (2023). Evaluation of Phytochemical Analysis and Invitro Antioxidant activities of Stem and Leaf extract of Andrographis echioides (L.) Nees. Biological Forum – An International Journal, 15(5): 636-646.