Formulation and Evaluation of Herbal Hair Growth Formulation of Ashwagandha in the Treatment for Alopecia

Author: Wagh Jyoti G., Pandhare R.B., Pawar A.R., Veerkar Prachi V., Amit Lunked and Katkar Rushikesh B.

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Abstract

Hair loss can be seen as a patchy, confluent, or diffuse pattern in alopecia. With a lifetime risk of 1.7%, the prevalence in the general population was estimated to be between 0.1% and 0.2%. Both men and women can have alopecia equally, but some studies have found that men are more frequently affected. At any age, it can happen. As a Rasayana, Withania somnifera (Ashawagandha) is a highly valued herb in the Indian Ayurvedic medical system (tonic). It is particularly utilised as a nervine tonic and for treating a variety of illness conditions. The relationship between ashwagandha and hair loss is still being researched in addition to all other applications. It can be strongly inferred from the current research that Aswhagandha may have ingredients that help promote hair development. It was concluded that the highest withanolide content was found in methanolic extract, which, when combined with a herbal gel base, can promote hair growth without irritating the skin. According to the overall findings of this exploratory study, using this herbal hair growth formulation for a short period of time might dramatically reduce hair loss and may even stimulate new hair growth in some people.

Keywords

Alopecia, Ashawagandha, withanolide, Withania somnifera, minoxidil

Conclusion

Forensic and clinical pathology may benefit from the current HPTLC approach. The strategy is important for in-process quality monitoring of plant raw materials since it is a sensible, cost-effective solution in the pharmaceutical and phytopharmaceutical industries. The methanolic extract was found to have more withanolide than any of the other extracts. The identification of withanolide in the gel formulation is supported by the indirect TLC-HRMS results of the sample and standards. This HPTLC indirect TLC-HRMS approach can be used for chemotaxonomy and phyllogenetic position of plant species as well as the screening and quantification of withanolides in crude plant powders, plant extracts, formulations, or in-process quality control in the phytopharmaceutical industry. The Aswhagandha may include ingredients that can stimulate hair development, according to the findings of an experiment on the activity of hair growth in rats. It is concluded that methanolic extract has the highest withanolide content and, when combined with a herbal gel base, can promote hair growth without irritating the skin. It demonstrated the shortest possible time for the growth of hair to begin and finish on denuded surfaces. In comparison to others, it was also discovered to increase hair length. Overall, the early study's findings indicate that using this herbal hair growth formulation for a brief period of time can dramatically reduce hair loss and, in some participants, even stimulate new hair growth.

References

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How to cite this article

Wagh Jyoti G., Pandhare R.B., Pawar A.R., Veerkar Prachi V., Amit Lunked and Katkar Rushikesh B. (2023). Formulation and Evaluation of Herbal Hair Growth Formulation of Ashwagandha in the Treatment for Alopecia. Biological Forum – An International Journal, 15(5): 853-858.