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Isolation of Anthraquinone from the Roots of North Western Himalayan Medicinal Plant Eremurus himalaicus Baker

Author: Sumaira Rashid, Fahim Bashir, Adil Gani and Bashir Ahmad Ganai

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Abstract

Eremurus himalaicus Baker, belonging to the Asphodelaceae family, is one of the least investigated valuable medicinal plant and is widely utilised in conventional and folk remedies as vegetable, for treating anaemia, and inducing lactation in post-partum period. In light of the pervasive use of E. himalaicus in traditional medicine and the paucity of research into its chemical constituents, the purpose of this study was to isolate and identify the characteristic secondary metabolite, anthraquinone. The air-dried underground part of the plant was investigated. Crude extract was obtained by successive hot extraction using Soxhlet apparatus. Using a wide range of chromatographic methods like Silica gel column chromatography and Thin Layer Chromatography, Aloechrysone was isolated from ethyl acetate and methanol fractions of the crude extract and structure elucidation was done by using spectroscopic techniques of NMR/MS. This identified phytoconstituent is the first report from E. himalaicus. Future research should be conducted to bridge the gaps in in vivo and in vitro study of this compound and pave the way for the clinical application of Aloechrysone.

Keywords

Eremurus himalaicus, Aloechrysone, NMR, MS, Compound isolation

Conclusion

This study is the first report on the isolation of Aloechrysone from the roots of E. himalaicus. Further research may be carried out for isolation of various other secondary metabolites from this under researched medicinal plant. Moreover, in vitro and in vivo studies of this compound can be carried out for establishing its pharmacological properties.

References

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How to cite this article

Sumaira Rashid, Fahim Bashir, Adil Gani and Bashir Ahmad Ganai (2023). Isolation of Anthraquinone from the Roots of North Western Himalayan Medicinal Plant Eremurus himalaicus Baker. Biological Forum – An International Journal, 15(4): 411-415.