Macaranga indica Plant Assisted Rapid Synthesis of Copper Nanoparticles for Biomedical Applications

Author: Gajanan Hegde and Tanuja Kadre

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Abstract

Rapid synthesis of stable copper nanoparticles is a challenging process in the synthetic world. Here in this study, the above challenge was achieved via the green route by using Macaranga indica plant extract. Macaranga indica is a medicinal plant widely available in the western ghat evergreen forest. Since a decade ago, villagers of the western ghat belt have been using its medicinal properties like antibacterial, antioxidant, antidiabetic, and antidysentery as household remedies. In this current study, we have used its bark extract to prepare stable copper nanoparticles to increase its medicinal properties. Synthesized nanoparticles are characterized by using analytical tools like UV-Vis spectra, XRD, TG, FESEM, EDX, and TEM analysis. These techniques reveal that synthesized nanoparticles are crystalline monodispersed in nature and have a size of 20-22 nm. Furthermore, these biocapped nanoparticles have shown good antibacterial and antioxidant properties and can be used for biomedical applications as well as in drinking water treatment.

Keywords

Rapid green synthesis, Copper Nano Particles, Macaranga indica, Microwave Assisted, Biomedical applications

Conclusion

In this study, employing M. Indica plant bark extract act as a reducing and stabilizing agent, the biocapped CuNPs of almost spherical form were successfully produced using microwave irradiation. The UV-Vis spectra for the SPR peak, 535 nm, are used to track the synthesis of CuNPs. With rising reaction mixture temperature, SPR intensity rose linearly. The marginal pH reduction and E increase of the reaction mixture provide evidence in favor of the CuNPs' production mechanism. According to UV-Vis spectra, the highest reduction, which converted 80% of the Cu2+ ions into CuNPs, occurred in less than 6 minutes, while the full reduction occurred in roughly 8 minutes. These CuNPs' structural and microstructural information was gathered utilizing the techniques of XRD, EDX, TG, and FESEM/TEM. The CuNPs' XRD pattern and reported statistics for copper metal coincided, and the crystal size is around 23 nm. The heat breakdown of plant waste materials and the oxidation of Cu to CuO are demonstrated by TG analysis. The homogeneous spherical particles created here are visible in FESEM/TEM pictures. As anticipated, the presence of Cu alone is confirmed by elemental analysis by EDX. The synthesized Macaranga indica bark extract-mediated copper nanoparticles have shown good antimicrobial properties and antioxidant properties compared with the standard drugs available in the market. Hence, this can be used in the biomedical field as a potent drug.

References

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How to cite this article

Gajanan Hegde and Tanuja Kadre (2023). Macaranga indica Plant Assisted Rapid Synthesis of Copper Nanoparticles for Biomedical Applications. Biological Forum – An International Journal, 15(5): 1610-1615.