Mesenchymal Stem Cells in Regenerative Medicine

Author: Pavitra Revadi Jain, Vivek R. Kasaralikar, Pradeepkumar H., B Roopali, Pavan, Manikya Sai Kiran and Sai Prasanna G.

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Abstract

Regenerative medicine's key tool is mesenchymal stem cells. Multipurpose mesenchymal stromal cells, multipotent stromal cells, medicinal signalling cells, and MSCs are various names for mesenchymal stem cells. The first isolation of human ESC (Embryonic Stem Cells) was reported in 1998. The osteogenic population of cells with fibroblast-like appearance that were isolated from bone marrow in 1968 is the first recorded evidence of adult multipotent cells, or MSC. The primary sources of MSCs are classified as adult, fetal, and embryonic cell types. MScs can be delivered intra-arterially, intra-lesionally, via multi-focal lesions, intravenous catheterization, and regional perfusion. MSCs can be clinically utilized in veterinary regenerative medicine to treat clinical conditions mostly associated with autoimmune, degenerative, and inflammatory diseases.

Keywords

Mesenchymal stem cells, Regenerative Medicine, tissue repair mechanism, multipotent cells, Intra-arterial delivery, multi-focal lesions

Conclusion

Regenerative Medicine is still in budding stage. Still preclinical trials are ongoing in the field so to gain the knowledge of regenerative medicine it is important to know the source, differentiating ability, routes of administration and clinical areas of MSCs.

References

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How to cite this article

Pavitra Revadi Jain, Vivek R. Kasaralikar, Pradeepkumar H., B Roopali, Pavan, Manikya Sai Kiran and Sai Prasanna G. (2023). Mesenchymal Stem Cells in Regenerative Medicine. Biological Forum – An International Journal, 15(10): 883-884.