Phytochemical Profiling and GCMS Study of Adhatoda vasica Nees. an Ethnomedicinal Plant of North Western Himalaya

Author: Rachna Verma*, Ashwani Tapwal** and Sunil Puri*

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Abstract

The ethnic people of the Himachal Pradesh have great faith in effectiveness of medicinal herbs. The ethnomedicinal plant Adhatoda vasica was analysed for its phytochemical, antimicrobial and antioxidant properties. The ethanolic extract of plant root was analysed against the standard and clinical isolates of five microbial strains viz. Staphylococcus aureus, Escherichia coli, Klebsiella pneumoniae, Salmonella typhimurium and Pseudomonas aeruginosa. The plant root extract showed maximum inhibition against clinical isolate of Salmonella typhimurium (13.3±0.5) at 200μg/ml concentration. The maximum antioxidant activity (38.55 ± 0.22) of root extract of plant was observed at 75μg/ml concentration and minimum (13.47±0.47) at 15μg/ml concentration. Standard analysis of phytochemicals in the root extract of plant showed presence of terpenoids, flavonoids, tannins, cardiac glycosides, alkaloids, reducing sugars and saponins. In GC-MS profiling the plant root extractshowed presence of imp

Keywords

Adhatoda vasica, north western Himalaya, antimicrobial, antioxidant, GC-MS profiling.

Conclusion

In conclusion, Adhatoda vasica is an important plant of north western Himalayas and is presently used for the treatment of asthma in the study area by the traditional practitioners. The scientific investigation of the plant included antimicrobial, antioxidant and preliminary phytochemical studies which suggests the presence of important phytochemical constituents in the plant extracts and which was further justified by the GC-MS analysis of the plant. The presence of various bioactive compounds in the Adhatoda vasica justifies the use of plant for various ailments by the ethnic people of north western Himalayas. From the results of the present study, it could be concluded that Adhatoda vasica contains various bioactive compounds of potential medicinal use and is a plant of pharmaceutical importance.

References

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How to cite this article

Rachna Verma, Ashwani Tapwal and Sunil Puri (2016). Phytochemical Profiling and GCMS Study of Adhatoda vasica Nees. an Ethnomedicinal Plant of North Western Himalaya, Biological Forum – An International Journal 8(2): 268-273.