Synergistic Efficacy of Centella asiatica and Andrographis paniculata in the Treatment of Gastroenteritis in Parvo Viral Infection with Special Reference to Oxidative Stress

Author: Lovelin Shweta Xaxa and Praveen Kumar

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Abstract

Parvovirus, or canine parvovirus, is a potentially fatal viral disease that affects dogs worldwide. There has been an alarming increase of up to 70% in cases due to the pandemic compared to the previous five years. So, this experimental study was designed to evaluate the antioxidant activity of herbal remedies used for the treatment of gastroenteritis and to document indigenous knowledge about these remedies. Our study involved 18 puppies suffering from gastroenteritis caused by parvovirus. They were divided into three groups by random selection T1, T2 & T3. Group T1 was treated with the combination of Andrographis paniculata and Centella asiatica, Group T2 was treated with Andrographis paniculata alone while the group T3 was treated with known sources of natural antioxidant Vit E & Se. The animals were regularly monitored and blood samples were collected on day 0, 3, 5, 7, 10 & 15 for hemato--biochemical and oxidative stress studies. Group T1 showed a marked improvement by the fifth d

Keywords

Pups, Andrographis paniculata, Centella asiatica, gastroenteritis, parvo viral infection, oxidative stress.

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