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Epidemiology and Clinical Manifestation of Hereditary Primary Microcephaly in General Population of Districts Karak and Bannu Khyber Pakhtunkhwa (KP), Pakistan

Author: Feroz Khan, Muhammad Ayaz, Abida Arshad, Fouzia, Hameed Ur Rehman, Amjid Ali, Sana Ashiq, Kanwal Ashiq, Haleema Sadia, Shahid Raza, Shafaat Hussain, Umair Ali, Abdul Wahab, Asfa Nazish, Aneela Riaz, Sehrish Khattak, Bilal Ahmad Zafar Amin and Kausar Malik

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Abstract

The present study was conducted during March to December 2017 in districts Bannu and Karak, to investigate the epidemiology of microcephalic patients. Total of 7 families with 29 affected individuals were studied. Among these one family was recorded from district Bannu and 6 were from district Karak. Affected male and female individuals were 18 (62.06%) and 11 (37.94%) respectively. Age and head size of the affected members of each families were calculated by using mean and standard deviation. This data would give us knowledge about their disease and to provide a cautious management strategy to fight against diseases. Additionally, it would also provide tools for researcher and clinicians seeking a better understanding of inherited primary microcephaly.

Keywords

Epidemiology, Clinical Manifestation, Hereditary Primary Microcephaly, General Population.

Conclusion

In conclusion we have established the incidence of inherited primary microcephaly in Pakistani population as well as their clinical features. This data would provide significance role in morbidity of human Pakistani population and would also provide cautious management strategy to fight against diseases. Additionally, it would give knowledge about their disease and provide tools for researcher and clinicians seeking a better understandingof inherited primary microcephaly.

References

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How to cite this article

Khan, F., Ayaz, M., Arshad, A., Fouzia, Rehman, H. Ur, Ali, A., Ashiq, S., Ashiq, K., Sadia, H., Raza, S., Hussain, S., Ali, U., Wahab, A., Nazish, A., Riaz, A., Khattak, S., Amin, B.A.Z. and Malik, K. (2019). Epidemiology and Clinical Manifestation of