Alteration in the Serum Cholesterol Level of Dams due to Intoxication of Mercuric Chloride and its Recovery by Ashwagandha and EPL

Author: Vishwas Tiwari

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Abstract

The recovery function of ‘Essential phospholipids’ (EPL) and Ashwagandha on Mercuric Chloride induced alteration in serum cholesterol levels of dams were investigated. Ashwagandha and EPL is considered as “Indian Ginseng” and remarkable antioxidant reduces toxic free radicals in the blood . Both Allopathic and Ayurvedic medicines may be beneficial in the recovery of intoxicated blood and significant clue for Hematological investigations. Animals were treated with 0.5 ppm aqueous mercuric chloride for a period of 7, 14 and 21 days. For the recovery 175mg of EPL and 35mg of Ashwagandha were administered to mice (Already treated with mercuric chloride) for a period of 7,14 and 21 days. Daily treatment of mercuric chloride decreased the cholesterol level in the blood of dams. Simultaneous administration of EPL and Ashwagandha significantly recovered the serum cholesterol level of dams. It appears that the protective effect of EPL and Ashwagandha against mercuric chloride increased serum level of cholesterol is mediated through antioxidative action of EPL and Ashwagandha. Thus, the serum level of cholesterol in all groups was increased.

Keywords

Dams (pregnant mice), EPL, Ashwagandha, Cholesterol, Mercuric chloride

Conclusion

The Synergistic recovery effect of EPL and Ashwagandha is remarkably observed in this investigation. The ‘Essential Drug” not only recovers the fluctuated level of Cholesterol but also reset the biochemical pathway of Cholesterol during biosynthesis. Secondly Ashwagandha, ‘The Indian Ginseng” through Anti-oxidative action not only keep the normal recommended level of Cholesterol in the blood but also reduces free radicals in the blood. (David et al., 2003; Tiwari and Bhattacharya 2004). Ashwagandha and EPL is considered as “Indian Ginseng “and remarkable antioxidant reduces toxic free radicals in the blood. Both Allopathic and Ayurvedic medicines may be beneficial in the recovery of intoxicated blood and significant clue for Hematological investigations in the Medical field. The recovery action of ‘Essential phospholipids’ (EPL) and Ashwagandha on Mercuric Chloride induced alteration in serum Cholesterol levels of dams were investigated. The overall recovery in the Cholesterol level was quite beneficial to protect against mercury intoxication. However, for therapeutic purpose further investigations are necessary.

References

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How to cite this article

Vishwas Tiwari (2023). Alteration in the Serum Cholesterol Level of Dams due to Intoxication of Mercuric Chloride and its Recovery by Ashwagandha and EPL. Biological Forum – An International Journal, 15(1): 554-558.