Histopathological Studies on Effects of Sublethal Concentrations of Lindane on the Hepatic Cells of Clarias batrachus based on Contaminant Concentration and Exposure Time

Author: Sehenaj Sultana

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Abstract

The study focuses on the overall toxicological impact of lindane; a persistent organic pollutant (POP), a commonly used pesticide (Hexachlorocyclohexane) on the liver tissues of Clarias batrachus. The fishes were exposed to sub-lethal concentrations of 0.2 mg/L, 0.4 mg/L, and 0.6 mg/L for 24 hours and 96 hours to study the comparative effects of the toxicant over different exposure periods. Vacuolations, pyknotic nuclei, infiltration, and fat deposition in hepatic cells were visible in the liver tissues. The concentration of pesticide and exposure period were found to have an increasing effect on the alterations detected. This confirmed the toxic effects of lindane in fish, which may eventually affect humans via the food chain.

Keywords

Clarias batrachus, lindane, liver, histological studies, pesticides, fishes

Conclusion

The findings imply that when lindane is persistent over time, even a small dose may result in physiological issues in fish. Pesticides shouldn't be permitted to enter the nearby wetlands, not even in trace levels. In order to determine the levels that are safe for the aquatic ecosystem and to search for environmentally friendly alternatives, more research is needed to assess the impact of lindane concentrations on the biology of various species. It has become essential to formulate stringent rules against the indiscriminate use of this pesticide. since the pesticide is present in the environment, organochlorine as a persistent organic pollutant may induce toxic effects in fish and other aquatic fauna. Consequently, there is a possibility that they may also reach humans through food chain contamination. It is, therefore a matter of great Public Health significance to regularly monitor the pesticide residues in food and humans to assess the population exposure to this pesticide.

References

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How to cite this article

Sehenaj Sultana (2023). Histopathological Studies on Effects of Sublethal Concentrations of Lindane on the Hepatic Cells of Clarias batrachus based on Contaminant Concentration and Exposure Time. Biological Forum – An International Journal, 15(1): 623-626.