Combination of Cinnamomum verum Bark Extract and Antibiotics: Potent Antimicrobial Activity

Author: Mitu Patel, Piyush Vyas, Jigar Patel and Poyam Patel

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Abstract

Antimicrobial substances derived from plants are not capable alone to fight completely against microorganisms due to several limitations in context resistant developed by the microbe. Continuous research has identified that antimicrobial substances derived from plants have been discovered to be synergistic enhancers, meaning that even while they may have fewer antibacterial activities when taken alone, but on combining with conventional medications, they increase the drug's efficacy. Antibiotics and plant extracts work together synergistically to combat resistant infections, opening up new options for the treatment of infectious disorders. Using the Agar well diffusion method, the synergistic interaction between plant extracts and antibacterial drugs was evaluated. According to the study's findings, there is a higher level of activity when Cinnamomum verum plant extracts are combined with antimicrobial compounds under examination. The findings of this study suggest that combining plant extract with antibiotics may be effective in battling newly developed drug-resistant microbes. The combination of the extract and the antibiotics did not result in the formation of any new compounds, according to HPTLC data.

Keywords

Cinnamomum verum, Plant Extract, Antibiotics, Antimicrobial, HPTLC

Conclusion

Effective antimicrobial activity against microorganisms has been demonstrated by plant extract. It can be used to enhance the antimicrobial activity of antibiotics and so as well we can reduce side effect of antibiotics by decreasing their concentrations.

References

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How to cite this article

Mitu Patel, Piyush Vyas, Jigar Patel and Poyam Patel (2023). Combination of Cinnamomum verum Bark Extract and Antibiotics: Potent Antimicrobial Activity. Biological Forum – An International Journal, 15(2): 580-585.