Comparative Study of the Cytotoxic Effects of Raw Aloe vera Gel Extract on the Root Tip Cells of Allium cepa and Allium sativum

Author: Rafia Farooquee and Dipankar Dutta

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Abstract

The Aloe vera plant is a succulent plant and its leaf is widely used in the field of cosmetic, Ayurvedic, Homeopathic Allopathic, as well as in food industry. The present study has been carried out to know about the cytotoxic effect of raw A. vera gel extract on the root tip cells of both Allium cepa (Onion) and A. sativum (Garlic). Three different concentrations of raw A. vera gel extract (i.e., 20%, 40% and 60%) were prepared for the experiment. The prepared microscopic slides were observed under a microscope. By summarizing the results using Analysis of Variance (ANOVA) it has been observed that the effect of 20%, 40% and 60% A. vera extract for the exposure of 24 hours on onion is higher than the garlic. Thus, the results of this study indicates that the raw A. vera gel extract exhibits some cytotoxic effect on both the root tip cells of A. cepa and A. sativum, but the effect of the raw gel extract is higher on onion root tip cells. Aloe vera has many beneficial effects and therefore, it was the most challenging part to establish its cytotoxic effect in terms of mitotic inhibition. Thus, we can conclude that the raw A. vera gel should not be consumed as it caused mitotic inhibition in both onion and garlic root tip cells.

Keywords

Aloe vera, Cytotoxic, Allium cepa, Allium sativum, Mitotic inhibition, Mitotic Index

Conclusion

The result of this study indicates that the raw Aloe vera gel extract exhibits some cytogenetic effect on both the root tip cells of onion (Allium cepa) and garlic (A. sativum), but the effect of raw A. vera gel extract on the root tip cells of onion is much higher than the root tip cells. Thus, by comparing the results obtained during this scientific investigation we can conclude that the effect of raw A. vera gel extract is higher in onion root tip cells than garlic root tip cells. Thus, we can say that onion is very much susceptible than garlic. From this scientific investigation we can also conclude that the raw A. vera gel should not be consumed as it causes mitotic inhibition in both garlic and onion root tip cells. A. vera gel also causes various mutagenic effects in some animals like in rats as mentioned by various researchers. So, the A. vera gel should be consumed after processing and not as raw product.

References

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How to cite this article

Rafia Farooquee and Dipankar Dutta (2023). Comparative Study of the Cytotoxic Effects of Raw Aloe vera Gel Extract on the Root Tip Cells of Allium cepa and Allium sativum. Biological Forum – An International Journal, 15(2): 990-1002.