Promising Effects of Solanum virginianum L Seed Extracts against the Oral Pathogens

Author: Rajaselvam J., Sobiya M. and Elaya Perumal U.

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Abstract

Dental caries is one of the emerging diseases in the world. It can be treated with antibiotics, but consumption of such synthetic antibiotics often could cause adverse effects on human health. To resolve these issues researchers, search natural resources for alternative sources. This study was done for analysing the antibacterial activity of Solanum virginianum L. seed extracts against the oral pathogens Staphylococcus mutans, Lactobacillus acidophilus, Pseudomonas aeruginosa, Streptococcus oralis, and Streptococcus mitis. In this study, S. virginianum L. seeds were collected and shade dried before making powder, and then the Acetone, Ethanol and Water were used for the extraction. Primary phytochemical constituents of the extracts were analysed and the antimicrobial activity was tested against the oral pathogens. The presence of phytochemicals could be the reason for the antimicrobial activity. Among all extracts, the aqueous extract showed the lowest activity against all the used bacteria. Acetone extract showed a maximum inhibitory zone against the bacteria S. mitis (35 mm) than the others. This study proves that S. virginianum seed extracts have active components to treat oral caries.

Keywords

Antimicrobial activity, Dental Cariogenic Bacteria, Dental pathogens, oral caries, phytochemical, Solanum virginianum

Conclusion

Nowadays herbal medicines are gaining popularity due to their cost-effectiveness, availability and effectiveness against a wide variety of microbial infections and eco-friendly nature. The results of our study show that Solanum virginianum L seed exhibits antimicrobial activity against dental cariogenic microbial flora such as Streptococcus mitis, Lactobacillus acidophilus, Streptococcus mutans, Streptococcus oralis and Pseudomonas aeruginosa. The results of our study revealed that the seed of S. virginianum L shows the presence of phytochemical compounds (flavonoids, saponins, coumarins, quinones, steroids, glycosides, proteins and carbohydrates). This study emphasized the promising cariogenic antimicrobial effect of S. virginianum L seed against the five important oral microorganisms compared to standard antimicrobial medicine. These findings give scientific insight into the traditional use of Solanum virginianum L seed as a mouthwash, a practice believed to prevent dental caries.

References

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How to cite this article

Rajaselvam J., Sobiya M. and Elaya Perumal U. (2023). Promising Effects of Solanum virginianum L Seed Extracts against the Oral Pathogens. Biological Forum – An International Journal, 15(2): 1070-1074.