Intravesical Therapy in Urinary Bladder Carcinoma

Author: Dhingra P., Khanduri P. and Singh S.

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Abstract

Urinary bladder carcinoma is associated with recurrence and metastasis. Various treatment modalities have been tried for treating this malignancy. However, there is variation in results reported in different studies. No particular treatment protocol has been reported to exhibit complete remission or limiting the progression of the disease. Intravesical chemotherapy is a novel technique that aids in preserving the urinary bladder from surgical mutilation while at the same time increases the disease free period and survival rates in these patients. The main challenge of intravesicle chemotherapy is patient selection process, and close monitoring of these subjects as there may be localized side-effects to this therapy. This review article presents an overview of various published articles in the field of intravesical chemotherapy of urinary bladder carcinoma.

Keywords

Intravesical, therapy, urinary, bladder, metastasis, carcinoma

Conclusion

Despite prolonging disease-free period of survival, neo-adjuvant intra-vesical chemotherapy has failed to show no distinct findings in long term or in preventing progression of superficial malignancy into invasive urinary bladder carcinoma. Also, there is limited data representing survival rate intra-vesical chemotherapy using any of the known chemotherapeutic agents.

References

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How to cite this article

Dhingra P., Khanduri P. and Singh S. (2023). Intravesical Therapy in Urinary Bladder Carcinoma. Biological Forum – An International Journal, 15(6): 39-43.