Evaluation of In vitro Antiulcer Activity of Ethanolic Extract of Pleurotus florida

Author: Sangeetha K., Senthilkumar G., Ambikapathy V. and Panneerselvam A.

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Abstract

Mushrooms have been playing an important role in several aspects of human activity. One of the most common culinary mushrooms is the oyster mushrooms. They are good sources of dietary fiber and other valuable nutrients. Pleurotus species is commonly known as giant mushroom. Edible ligninolytic mushrooms with high medicinal properties using the biotechnological and environmental field. It is an abundance of protein, minerals and elements of C and B complex. They are frequently as a therapeutic food having anticarcinogenic, anti cholestrolaemic and antimicrobial properties and also prophylactic properties. The present study investigates the antiulcer properties of edible mushroom Pleurotus florida, commercially cultivated in Trichy, Tamilnadu. The acid-neutralizing capacity (ANC) method and the H+/K+ -ATPase inhibitory activity methods were used to test the antiulcer activity of an ethanol-based extract of grown, dried, and powdered mushrooms. Results indicated that the ethanolic extract, with respect to H+/K+ - ATPase inhibitory action, extract considerably reduced ANC to 10.7 at a concentration of 1500 mg compared to standard, and at a concentration of 200 g compared to 60.8% with standard Omeprazole.

Keywords

Mushroom, Pleurotus florida, antiulcer activity, acid -neutralizing capacity, H+/K+ -ATPase inhibitory action, ethanol extract

Conclusion

In accordance to the outcomes of the current investigation, P. florida ethanolic extract was shown to have the most potential antiulcer agent. Analysing findings, the investigators led to the premise that Pleurotus florida's ethanolic extract may be used as a source of antiulcer medications. This study showed that mushrooms can be used for both food and medicine (Tundis, et al., 2008; Vyawahare et al., 2009; Zayachkivsk et al., 2005) and that they may be a good natural antiulcer alternative to currently available synthetic antiulcer medications in the food and pharmaceutical industries (Yalinkilic et al., 1994). Nevertheless, a thorough investigation of the bioactive components from Pleurotus florida and their mode of action, which is accountable for their antiulcer efficacy, needs to be done in the future.

References

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How to cite this article

Sangeetha K., Senthilkumar G., Ambikapathy V. and Panneerselvam A. (2023). Evaluation of In vitro Antiulcer Activity of Ethanolic Extract of Pleurotus florida. Biological Forum – An International Journal, 15(6): 211-214.