Therapeutic Management of Canine Diabetes Mellitus using Combination of Insulin and Momordica charantia Capsules

Author: Dilip Singh Meena, Nazeer Mohammed, Kartar Singh, Aarif Khan, Pradeep Kumar, Subhash Chand Meena and Vishambhar Dayal Sharma

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Abstract

This study's goal was to find out the effect of Momordica charantia capsules, insulin hormone and a high-fiber diet on the treatment of diabetic dogs. The study included eight client-owned dogs with naturally occurring diabetes mellitus. All dogs were given restricted fat, high-fiber diets and daily subcutaneous insulin injections. Momordica charantia capsules were given orally to four dogs in the treatment group at a dosage of 200 mg/kg body weight (BW) every 12 hours along with insulin for 21 days after that only Momordica charantia capsules orally administration for two months. The control group of four dogs only received insulin therapy. The fasting blood glucose concentrations were significantly lower after taking Momordica charantia capsules (200 mg/kg body weight/day) for 2 months compared to the control group and before treatment. In conclusion, the use of glycemic control was enhanced more effectively by the use of the Momordica charantia capsules at 200 mg/kg BW/day when paired with a low-fat, high-fiber diet than by the use of insulin alone in diabetes treatment. The main challenge regarding herbal therapy in canine diabetes mellitus is that its effects are varied according to individual animal blood glucose concentration levels and also take a long time to show their results.

Keywords

Diabetes, Dogs, Glucose, Insulin, Momordica charantia

Conclusion

In combination with insulin and Momordica charantia capsules at a dosing rate of 200 mg/kg/day effectively reduced blood fasting glucose concentration. Momordica charantia capsules demonstrated an insulin-mimetic action and could enhance glycaemia management in naturally occurring diabetes when combined with insulin therapy and a low-fat, high-fiber diet.

References

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How to cite this article

Dilip Singh Meena, Nazeer Mohammed, Kartar Singh, Aarif Khan, Pradeep Kumar, Subhash Chand Meena and Vishambhar Dayal Sharma (2023). Therapeutic Management of Canine Diabetes Mellitus using Combination of Insulin and Momordica charantia Capsules. Biological Forum – An International Journal, 15(5a): 203-208.