Biological Evaluation of Artocarpus altilis (Parkinson) Fosberg

Author: Meera Sabari V., Beena Lawrence, T. Citarasu, Mithuna S.K., Adarsh Shiju S., Gayathri V.J., Saran Babu B.

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Abstract

An emerging infectious disease is an infectious disease whose incidence has increased in the past 20 years and could increase in the near future. Search for therapeutic drugs against these diseases is progressing and is the need of the hour. Therefore, the present study was conducted to evaluate the bioefficacy of Artocarpus altilis fruits against various human pathogens such as Klebsiella pneumonia, Streptococcus mutans, Lactobacillus sps, Bacillus subtilis and Enterococcus faecalis and also to determine the presence of active compounds in the fruit through GC MS analysis. Further more, molecular docking was also conducted to study the interaction of molecules. Klebsiella pneumonia and Streptococcus mutans were found more sensitive towards fruit extract with a zone of inhibition of 19mm. The major peak area percentage reported through GC MS analysis was 12.75 and the corresponding compound was found to be Tris ( tert-butyl dimethylsilyloxy).

Keywords

Artocarpus altilis, Bioefficacy, GC MS

Conclusion

The present study revealed the bioefficacy of Artocarpus altilis (Parkinson) Fosberg fruits in terms of antimicrobial activity brought about by the presence of various compounds detected by GC MS.

References

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How to cite this article

Meera Sabari V., Beena Lawrence, T. Citarasu, Mithuna S.K., Adarsh Shiju S., Gayathri V.J., Saran Babu B. (2023). Biological Evaluation of Artocarpus altilis (Parkinson) Fosberg. Biological Forum – An International Journal, 15(5a): 549-552.