A Study on Evaluation of Antipyretic and Analgesic Activities of Curcuma longa Extract

Author: Keshamma E.

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Abstract

Turmeric has been used for centuries in many indigenous medical systems, including the Ayurvedic systems, to treat inflammatory diseases and human afflictions. Hence, the present study was conducted with the main objectives of evaluating the antipyretic and analgesic activities of rhizome extract of Curcuma longa. Rhizome of C. longa was subjected to successive solvent extraction by continuous hot extraction (Soxhlet) with ethanol. Brewer's yeast's antipyretic and acetic acid induced writhing test was used for the evaluation of antipyretic and analgesic effects of ethanolic rhizome extract of C. longa respectively. Results depicted that writhing inhibition (%) and antipyretic effect of ethanolic rhizome extract of C. longa at the concentration of 25 µl/L and 100 µl/L respectively was found to be at par with that of positive control i.e., standard Diclofenac sodium drug. In conclusion, our study results clearly demonstrated that ethanolic rhizome extract of C. longa exhibited antipyretic and analgesic activities. Hence, rhizome of C. longa could be considered for development natural antipyretic and analgesic drugs.

Keywords

Curcuma longa, Rhizome, Extract, Antipyretic, Analgesic

Conclusion

The results of present study clearly demonstrated that ethanolic rhizome extract of C. longa exhibited antipyretic and analgesic activities. Hence, rhizome of C. longa could be considered for development natural antipyretic and analgesic drugs. However, further studies are recommended to be carried in-vivo model for further evaluation of efficacy and to elucidate the exact mechanism of action responsible for antipyretic and analgesic activities of rhizome of C. longa.

References

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How to cite this article

Keshamma E. (2023). A Study on Evaluation of Antipyretic and Analgesic Activities of Curcuma longa Extract. Biological Forum – An International Journal, 15(2): 1296-1299.