Comparative Hemato-biochemical Evaluations of Canine Pyometra

Author: Renuka Mishra, Pankaj Chayal, Neeti Kopal Bante and Sunil Kumar Meena

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Abstract

Canine pyometra results in the accumulation of pus in the progesterone-influenced uterus of unmated canines. Clinical symptoms like purulent vaginal discharge, abdominal pain, lethargy, depression, anorexia, polyuria, polydipsia and vomiting are observed. Without timely treatment, it can progress to peritonitis, sepsis, nephritis, and the dysfunction of multiple organs. Systemic effects of canine pyometra can be indicated by various hemato-biochemical parameters. Sixteen female dogs with open and closed pyometra of various breeds, ages ranging between 2-12 years, were examined on clinical aspect at City Teaching Veterinary Clinical Complex, College of Veterinary Science and Animal Husbandry, Anjora, Durg, Chhattisgarh. The suspected diagnosis was based on history taken from owners and overt clinical signs which were later confirmed by transabdominal ultrasonographic examinations. Analysis of Haemato-biochemical parameters before starting the treatment protocols in all the pyometra-affected dogs was performed. Approximately, three milliliters of blood were collected from cephalic and saphenous veins aseptically in EDTA-containing vials (TLC and Hb) and clot-activated vials (BUN and Creatinine) for hemato-biochemical evaluation. An increase in the number of leucocytes and reduced hemoglobin concentration were found in canine pyometra. Increased creatinine and BUN values show compromised efficiency of kidneys in filtering nitrogenous wastes from the blood circulation in pyometra-affected dogs.

Keywords

Haemoglobin, BUN, White blood cell count, Canines, Pyometra, Creatinine

Conclusion

Pyometra is a multifactorial disease that commonly occurs during the diestrus phase of female canines. An increase in the number of leucocytes and reduced hemoglobin concentration were found in canine pyometra. Increased creatinine and BUN values show compromised efficiency of kidneys in filtering nitrogenous wastes from the blood circulation in pyometra-affected dogs.

References

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How to cite this article

Renuka Mishra, Pankaj Chayal, Neeti Kopal Bante and Sunil Kumar Meena (2024). Comparative Hemato-biochemical Evaluations of Canine Pyometra. Biological Forum – An International Journal, 16(1): 72-75.