Therapeutic Management of Open Pyometra in Canines

Author: Neeti Kopal Bante, Renuka Mishra, S.K. Maiti, Shraddha Sinha, Saleema Ahmed Quadri and Pankaj Chayal

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Abstract

When reproductive activity is desirable, conservative medical treatment is a possibility, but there is a risk of recurrence. The present study was designed to evaluate the efficacy of various treatment protocols for open pyometra in canines. The study was conducted in the Teaching Veterinary Clinical Complex, College of Veterinary Science and Animal Husbandry, Anjora, Durg, Chhattisgarh. The suspicion of open pyometra was based upon the history of diestrus, mating without conception 15 days earlier, and clinical signs of inappetence or anorexia, lethargy, polyuria, polydipsia, vomition, nausea, and vulvar discharge were observed. These dogs were divided into 4 groups having 4 animals affected with open pyometra in each group based on different treatment protocols followed for its therapeutic management. The treatment protocol followed for groups I, II, III, and IV were Parentral Antibiotic + Intrauterine flushing, Parentral Antibiotic + Intrauterine flushing + Misoprostol, Parentral Antibiotic + Intrauterine flushing + PGF2α and Parentral Antibiotic + Intrauterine flushing + Misoprostol + PGF2α, respectively. The efficacy of treatment protocols was evaluated based on the percentage of animals recovered or unrecovered in groups of different treatment protocols. The treatment response was found to be 100% in all hormonally treated groups and 50 % in the remaining group of open pyometra-affected dogs. It can be concluded that the administration of prostaglandin F2α along with prostaglandin E1 (misoprostol) resulted in increased uterine contraction with expulsion of uterine contents and cervical dilatation. The recurrence of pyometra was thought to be more in prostaglandin F2 and E1 treated dogs due to hormonal imbalance during the estrus cycle.

Keywords

Intrauterine flushing, Parenteral Antibiotic, Misoprostol, PGF2α

Conclusion

It can be concluded that the administration of prostaglandin F2α along with prostaglandin E1 (misoprostol) resulted in increased uterine contraction with expulsion of uterine contents and cervical dilatation in a shorter duration of time. The recurrence of pyometra was thought to be more in prostaglandin F2 and E1 treated dogs due to comparatively more hormonal manipulation during the estrus cycle, but recovery was quite effective.

References

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How to cite this article

Neeti Kopal Bante, Renuka Mishra, S.K. Maiti, Shraddha Sinha, Saleema Ahmed Quadri and Pankaj Chayal (2024). Therapeutic Management of Open Pyometra in Canines. Biological Forum – An International Journal, 16(1): 85-88.