Advanced Metabolomic Profiling of the Spray-dried Cow Milk Powder using a High-Resolution Accurate Mass Spectrometer

Author: Shankar Lal, Sohan Lal Bajya, Mahendra Kumar, Mahendra Kumar, Saurabh Bondre and Ajeet Kumar Upadhyay

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Abstract

This study presents an in-depth metabolomic and spectroscopic analysis of spray-dried cow milk powder, utilizing high-resolution accurate mass spectrometry (HRMS) and Fourier-transform infrared (FTIR) spectroscopy. Advanced HRMS techniques were employed to identify and quantify a wide range of metabolites, including amino acids, lipids, carbohydrates, and organic acids, revealing significant variations in their concentrations compared to fresh milk and other drying methods. Notable findings include reductions in essential amino acids and increases in oxidative lipid products, attributed to the thermal stress of spray drying. The FTIR analysis further confirmed the presence of key components such as proteins, lipids, and lactose, providing a molecular fingerprint of the cow milk powder. The comprehensive data highlights the chemical transformations induced by the spray drying process, underscoring the need for process optimization to preserve dairy powders' nutritional and functional properties. This research contributes valuable insights for enhancing the quality and efficacy of cow milk powder in the food industry

Keywords

Cow milk powder, Spray Drying, Metabolomics, High-Resolution Mass Spectrometry, FTIR Spectroscopy

Conclusion

This study successfully utilized high-resolution mass spectrometry (HR-MS) and FTIR spectroscopy to comprehensively profile the biochemical and molecular landscape of spray-dried cow milk powder. The analysis revealed significant alterations in amino acids, lipids, and carbohydrates due to the thermal impact of spray drying. The findings underscore the need for optimizing drying processes to preserve the nutritional and functional quality of dairy powders, thereby enhancing product efficacy and consumer health benefits. HR-MS is highly accurate, reliable and sensitive analytic technique to detect the compounds and metabolomics in milk and milk products

References

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How to cite this article

Shankar Lal, Sohan Lal Bajya, Mahendra Kumar, Mahendra Kumar, Saurabh Bondre and Ajeet Kumar Upadhyay (2024). Advanced Metabolomic Profiling of the Spray-dried Cow Milk Powder using a High-Resolution Accurate Mass Spectrometer. Biological Forum – An International Journal, 16(8): 151-155.